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Unfortunately, the test proved to be too complicated and unwieldly for many patients and their clinicians as it required "an overnight fast, ingestion of (modestly) radioactive cobalamin, a 24-hour collection of urine, a cobalamin injection, two trips to the laboratory, and, if the result [was] abnormal, repetition of the entire procedure with a dose of [intrinsic factor]" (45)
Individuals with Wilson's disease or copper metabolism disorders should avoid GHK-CU entirely
If IGF-1 remains below the mid-reference range, the dose may be increased to the 500 mcg ceiling
Lasting tiredness can have many causes beyond B12, such as iron levels, thyroid issues, or sleep problems, and a check-in helps make sure you are treating the right thing
